A Research Study On Breast Cancer - 2138 Words

Introduction Breast Cancer accounts for more than 20 percent of cancer in women, and is the primary cause of cancer death among women globally.1 Despite extensive scientific research on the disease, the outlook on a cure arguably remains poor. While some breast cancer survivors and women at high risk remain hopeful that soy intake will reduce the risk or even cure cancer, the recommendations are conflicting. For decades, the relationship between soy foods, supplements, phytoestrogen intake and cancer has prompted considerable debate for scientists and clinicians. Patients with breast cancer are frequently advised to avoid soy foods.2 And, the American Cancer Society recommends â€Å"breast cancer survivors consume only moderate amounts of†¦show more content†¦9,10 (See Table 1.1) Table 1.1: Isoflavones (mg) in Soy Foods Food #mg 60 g textured vegetable (soy) protein 45 mg  ½ cup miso 59 mg  ½ cup soybeans, boiled 47 mg 3 oz tempeh 37 mg 1 cup soy milk 30 mg 3 oz tofu 20 mg Source: USDA Nutrient Data Laboratory There are many proposed mechanisms that attempt to explain how the phytochemicals in soybeans exhibit anti-carcinogenic activity. We do know that genistein affects microRNA expression – targeted translation inhibitors for multiple proteins implicated in the regulation of various pathobiological processes in cancer.11 Lignans include matairesinol and secoisolariciresinol, which are transformed by intestinal bacteria into estrogenic compounds. Lignans are found in flax seeds, whole-wheat flour, tea, some fruits and other cereal grains.4 They are found in the woody portions of fruits and vegetable, in seed coats and in grain bran of fiber-rich cereals.5 Phytoestrogens are ingested in their natural beta- glycosidic forms. The beta glycosidic forms are hydrolyzed to their aglycones in the intestine, absorbed, and then linked in the intestinal wall and live with glucuronic acid to make them more water-soluble.12,13 These metabolites of isoflavones preodominate in blood and urine.4 Isoflavones are excreted from the body within 24 hours after ingestion. On theShow MoreRelatedA Research Study On Breast Cancer1308 Words   |  6 PagesIntroduction Breast Cancer is on the fore-front of modern tumor research and scientists are continually seeking for new ways to treat and prevent cancer progression. Current treatments by hormone-dependent drugs like Tamoxifen and Raloxifene focus on estrogen receptor inhibition in mammary and endometrial cell lines. This group of drugs are known as selective-estrogen receptor modulators or SERMS, which are effective in estrogen-receptor positive (ER+) and hormone-estrogen receptor 2 positiveRead MoreA Research Study On Breast Cancer981 Words   |  4 PagesIn this case study we have Sarah a forty-two-year-old woman who has breast cancer which has metastasized to her lungs. Despite having had multiple tumors removed the cancer has returned. Sarah’s oncologist, Greg, recommends that she take part in a double blind experimental drug trial in an effort to slow the occurrence of more tumors. Greg explains that the risks of the drug are not entirely known; the drug won’t cure her c ancer but may slow its progression, it may leave her extremely fatiguedRead MoreA Research Study On Breast Cancer1702 Words   |  7 PagesIntroduction Breast cancer is one of the leading causes of high mortality and morbidity in women population worldwide. Up to date, no effective breast cancer treatment has been developed and this has motivated academic scientists for the quest for alternative drugs and the discovery of drug targets. Increasing evidence suggests that carotenoids, which are micronutrients in fruit and vegetables, reduce breast cancer risk [1]. Previous findings suggest a protective role of ÃŽ ±-carotene, ÃŽ ²-carotene,Read MoreBreat Cancer Screening Essay1514 Words   |  7 PagesBREAST CANCER SCREENING DR. DANA MORTEZ ARLECIA PURVIS JULY 17, 2011 Current research shows mammograms are stronger than in the past. In a recent study it has confirmed that mammograms benefit for women in their forties and fifties. Women feel confident about the benefits that are associated with a regular mammograms for finding cancer early. However, mammograms can have their limitations. A mammogram will miss some cancers, and it sometimes can leadRead MoreA Short Note On Soy Products Good Or Bad For Cancer?1100 Words   |  5 PagesPeBenito 12/5/14 Bio 100 Section-09 Lynne Dowdy Soy Products Good or Bad for Cancer? Cancer is a disease that has been an ongoing controversy on what can help to prevent getting it. Cancer is when cells are dividing at an uncontrollable rate. Cancer is developed when cancer cells go into lymph nodes and also when they take over the blood vessels, lymph nodes are when there is swelling the the lymphatic system. With the cancer there is swelling which is called a tumor. Tumor is when there is swellingRead MoreThe Issue Of Breast Cancer830 Words   |  4 PagesThe issue of breast cancer affecting many individuals is a growing one. At the present time period it is now found that one in every eight women will be told they have breast cancer (â€Å"National Breast Cancer Foundation†, 2012). Therefore there is a significant amount of research going into this area. In addition, to the large amount of women and smaller amount of men who will be potentially diagnosed with breast cancer has become a global burden because those with metastatic cancer will eventuallyRea d MoreThe Survival Rates Of Breast Cancer1373 Words   |  6 Pages Breast Cancer is the most common misfortune in women and second leading cause of death by cancer. Today, woman with breast cancer have a 90% chance of surviving for five years post-diagnosis. However, African American women have a national survival rate of 79%. Socioeconomic barriers and lack of access to health services have crippled African American women in breast cancer advancements. Studies have show that African American women tend to be diagnosed with a higher-stage of cancer because ofRead MoreThe Importance Of Breast Cancer Treatment934 Words   |  4 PagesBreast cancer treatment depends on many factors such as the location of the cancer, the size, if it’s spread and the patient’s general health. Also, treatment currently includes surgery, chemotherapy, radiotherapy, hormonal therapy and targeted cancer drugs (Cancer Research UK, 2017a). Further, surgery includes lumpectomy which removes just the cancerous area in an attempt to keep the majority of the breas t tissue and has a much shorter recovery time and mastectomy which removes the entirety of theRead MoreA Brief Note On The North Fork Of Long Island1726 Words   |  7 Pagesweeds, these commodities would be much harder to come by. Chemicals such as PCB’s, PHA’s, and the now banned DDT were all once used on these fertile farmlands of Long Island and since then may be a direct factor to the rise in cancer rates on Long Island, especially breast cancer. In the agricultural industry, one of the most common ways to treat crops is by a fogging method. With this method, a large factor goes through the crops with tanks of whatever chemical pesticide or fungicide they may be usingRead MoreBreast Cancer : A Common Malignancy1204 Words   |  5 PagesBreast cancer is the most common malignancy in the UK, accounting for 15% of all diagnosed cancers, affecting around 50,000 women and 350 men, leading to just under 12,000 deaths in 11/12.1,2 The risk of getting breast cancer is linked to increased age, gender genetics (BRCA 1 BRCA 2 gene mutations). Lifestyle factors that also increase the incidence of breast cancer (around 27% each year) are; Oestrogen exposure, being overweight/obese, high alcohol intake, tobacco smoke, oral contraceptives